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thanx.
I ask a question and disappear...thanx for the answer. As I said, that is what I thought....
Factor VIIa (recombinant) promotes hemostasis by activating one of the pathways your body uses to form clots (extrinsic for thoses who understand this stuff). It forms a complex with tissue factor that is exposed at sites of injury and causes activation of different coagulation (clotting) factors. Through a few more steps a hemostatic (clot) plug gets formed and hemostasis (cessation of bleeding) hopefully occurs.
It is great for coagulopathic bleeding, not surgical bleeding. It will not stop an artery from bleeding out.
It is easy to carry...it stays in powder form until used and is mixed with sterile water.
Studies are equivical as to if it really works in trauma but I am a believer and have used it multiple times. They are going to start a large multi=center trial soon in the US. It is costly though...around 6000-10,000 a dose depending on the size of the patient and the amount used...
doc t.
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