Breast Cancer Vaccine?

[alelks]

This is a very interesting article. It amazes me that they can't find funding for human trials even from some very high profile agencies. It's just like everything else I guess. If you prevent it money can't be made for a cure once you get it.

Thoughts?

http://www.wndu.com/home/headlines/B...173738701.html

[SF_BHT]

Let's stop giving funding for a lot of the silly research programs that are earmarks and use some funding for this research.

[PedOncoDoc]

I will refer to my earlier post about our incredible ability to cure cancer in mice that rarely translates into successful human treatment strategies.

Having said that, Dr. Tuohy's concept of a vaccine against a protein only present during lactation is a novel and interesting idea. Given the amount of funds going to breast cancer and prostate cancer research/medical care, I'm surprised they haven't bit on this trial. Of course, I've not had the chance to see all of the data or the grant proposals, so there may be concerns about the science and/or its safety in/applicability to human trials. One safety concern would be significant side effects/toxicity in the case of pregnancy (unintentional or otherwise) after vaccination.

[Flicka]

Thank you for sharing this article - I'll definitely pass it on to some folks who will be able to give donations to the cause.

It amazes me - we have done so much research and learned so much on preventative care that is not being utilized or even publicized. I wrote an article (for a persona blog/site) on the benefits of saurkraut and learned that women who emmigrated from Poland to the United States were 3x more likely to develop breast cancer. This was attributed to changes in their diet - specifically, they consumed much less cabbage in the United States than when they were living in Poland. Cabbage and other veggies in the cabbage family contain incredible compounds and vitams that kill "bad" immune T cells, help increase the production of healthy T cells, target free radicals in the blood stream, and neutralize as well as remove chemo-resistant cancer cells from the body. Women suffering from breast cancer who included cabbage in their diet (at least 3x weekly) are also more likely to overcome it. There is application here for use in people with auto-immune diseases too. That's just one example of information people who are prone to these illnesses and cancers can learn and utlize to protect themselves, keep their health bills down, and decrease the burden on our health care system.

With so little funding available for this vaccine and other preventative treatments - it makes me wonder how much revanue drug companies will lose if these pro-active treamtents work, and if they have a hand in this.

Edited:
*Article stated that women were 3x more likely to develop breast cancer, vs 50% more likely (as I stated.) That specific statitistic/article may or may not have been total crap.
*Disclaimer: I am not a medicial professional. I write a personal outlook and nutritonal blog for others suffering from chronic auto-immune diseases.

[PedOncoDoc]

Originally Posted by Flicka

I wrote an article on the benefits of saurkraut and learned that women who emmigrated from Poland to the United States were 50% more likely to develop breast cancer....
...Cabbage and other veggies in the cabbage family contain incredible compounds and vitams that kill "bad" immune T cells, help increase the production of healthy T cells, target free radicals in the blood stream, and neutralize as well as remove chemo-resistant cancer cells from the body...

As I do research in immunology, I would love to read these peer-reviewed articles. I'm particularly interested in the statement of cabbage contents that overcome chemoresistance (does this function similarly to T cells coexpressing CD161, CD117 and IL-18Ra - Turtle et al, Immunology 2009)and kill "bad immune T cells". Could you please provide references?

Also, please define "bad immune T cells" - to what specific T cell subset are you referring are you referring? Cytotoxic CD8+ T cells that are directly cytotoxic and utilized to fight cancer in the setting of allogeneic stem cell transplantation (my clinical field), Th1, Th2 or Th17 CD4+ T cells, regulatory T cells? Some other T cell subset?

[Stiletto11]

There is a company called TapImmune under the ticker symbol TPIV that is currently in the early trial stages for a breast cancer treatment that only destroys the cancer cells. So far, although early, has been successful and is continuing to the next stage.