Old 10-06-2004, 20:10   #1
greg c
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Vioxx users...

Haven't seen this on the board, but it is a relevant and evolving situation- for the whole class of medications.

http://content.nejm.org/cgi/content/...ct/NEJMp048286

http://content.nejm.org/cgi/content/...ct/NEJMp048288
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Old 10-06-2004, 20:28   #2
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Quote:
Originally Posted by greg c
Haven't seen this on the board, but it is a relevant and evolving situation- for the whole class of medications.

http://content.nejm.org/cgi/content/...ct/NEJMp048286

http://content.nejm.org/cgi/content/...ct/NEJMp048288
It might be evolving to you but for me it's over.....

Vioxx has been removed from the market.

Team Sergeant
former Poster Boy for Vioxx.....
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Old 10-06-2004, 20:34   #3
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Quote:
Originally Posted by Team Sergeant
It might be evolving to you but for me it's over.....

Vioxx has been removed from the market.

Team Sergeant
former Poster Boy for Vioxx.....
Yo tambien, and after reading that, I am considering alternatives for the Celebrex they gave me to replace it.

It was nice to take one low dose, low stomach upset pill, once daily, but looks like there are good reasons not to use any of the COX2 inhibitors now.

I may be back to burning holes in my stomach with Ibuprofen and using narcotics when it gets really bad.

Bummer.

TR
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Old 10-06-2004, 20:41   #4
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celebrex and vioxx have the same basic mechanism of action and it is now being questioned whether the other two cox-2 inhibitors (celebrex and bextra) will have the same side effect if the studies are done to assess for this. Studies necessary to pass FDA approval don't typically have the patient numbers to bear out certain side effects... it was a study looking at vioxx for decreasing the incidence of colonic polyps that began to show an increased incidence in cardiac/cerebral events...

I would be cautious about using the drugs until further testing occurs... if it occurs.

doc t.

TR I asked Doc T to address this when I saw your post... as I saw you're in the same situation I currently in.... and I'm back on motrin....

TS
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Old 10-06-2004, 20:46   #5
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Doc T:

Isn't it possible to take something to control the impact on the stomach from taking ibuprofen constantly, like prilosec or whatever?

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Old 10-06-2004, 20:59   #6
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Damn! So much material here I don't know where to start.
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