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Old 03-23-2005, 15:39   #2
Eagle5US
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Join Date: Jan 2004
Location: Tampa
Posts: 2,544
Post This condition sucks

Sorry you have had to deal with this Sigi...

Your questions mirror those of other patients as well as clinicians. I have treated a few folks with this condition and researched it at length.

There is a thought that there is a genetic predisposition to cyctic acne between family members (Mother to Daughter)
Without going into the associated secondary infections that can occur as a result of the condition itself...there is a general concensus on the stages of lesion development:

1. Keratinous plug within the apocrine duct
2. Dilatation of the duct and associated hair follicle
3. Severe inflammatory changes in the specific single apocrine gland
4. Bacterial growth within the dialted duct
5. The duct grows to point of rupture-spreading the infection and inflammation
6. #5 results in extension of the supperation and tissue destruction
7. Finally ulceration and fibrosis with associated sinus tract formation

I know this does'nt tell you the why (basically because noone really knows), but it may help you a little with the how.

Hope this helps...all my best.

Eagle
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