It's common practice in my part of the country to shoot them on sight. I have witnessed several times of them trying to get a calf away from a mama cow. The ranchers do not like them for sure.
They are well aware of their target status and when they see a pickup they are hauling ass. They might stop 600yds out or so and see if you were really a threat, sometimes.
Eradication of ground squirrels and prarie dogs are fun sports here too.