No experience with these, but as a fellow that needs glasses...
If I were to get them, I'd go with the mixed color set.
The MEPRO R4E sights are offered in (4) configurations:
- Green Front, Green Rear sights
- Green Front, Orange Rear sights
- Orange Front, Green Rear sights
- Orange Front, Orange Rear sights
My fear is that a single color set could easily get blurred (c attached) in a hi-stress scenario.