Quote:
Originally Posted by Underwhelmed
http://journals.lww.com/anesthesiolo...lgesia.11.aspx
Not the original source I read this from, I think it was in Tintinalli, but I found this almost instantly.
[A few mins later...]
Whew, good thing I have a copy of Tintinalli in my home. It wasn't in there, but I WILL find where I got that information.
I remember it as being particularly shocking, a few months ago I overheard a vet talking to one of her techs about using narcan for ketamine, and I thought to myself "Hah! She clearly dosen't know how ketamine works." Later out of curiosity, I did some research on it, and sure enough they found that Ketamine had some action on optiate receptors at hypnotic doses. This seems counterintuitive, being that one of the strong points of ketamine is that it ISN'T an opiate and thus does not carry the same undesirable side-effects... but anyway, I'll keep working on it because I know the type of fire I'll be under if you don't see more proof. 
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The sign of a competent learner and educator...have a basis of supportive evidence. Thanks for the abstract, I had no idea it was that mechanism (in the non-human brain!!!!) . Hopefully you can dig up the reference...we are all here to learn.
ss
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'Revel in action, translate perceptions into instant judgements, and these into actions that are irrevocable, monumentous and dreadful - all this with lightning speed, in conditions of great stress and in an environment of high tension:what is expected of "us" is the impossible, yet we deliver just that.
(adapted from: Sherwin B. Nuland, MD, surgeon and author: The Wisdom of the Body, 1997 )
Education is the anti-ignorance we all need to better treat our patients. ss, 2008.
The blade is so sharp that the incision is perfect. They don't realize they've been cut until they're out of the fight: A Surgeon Warrior. I use a knife to defend life and to save it. ss (aka traumadoc)
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