[mugwump]

This is a common problem w/ fentanyl patches, especially with the higher dose/larger ones. The upper, inner thigh is sometimes the best site depending upon body type.

When we ran clinical trials of patches we used Johnson and Johnson Bioclusive Transparent Dressing, 4" x 5" to cover the patches. 3M Biopore tape is also an option if it's tolerated.

Another thing, all fentanyl patches are not equal. Try the original Johnson and Johnson ones, they have the best adhesive, better than the Howard, etc. ones. I belive J&J fentanyl patches include the dressing I referenced or will mail them to you free upon request.